How can hairy ears be inherited

The hairy ears trait consists of long hairs growing from the helix of the pinna; see Dronamraju and Stern et al. NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine.

While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.

Printed: Nov. To ensure long-term funding for the OMIM project, we have diversified our revenue stream. We are determined to keep this website freely accessible. Unfortunately, it is not free to produce. Expert curators review the literature and organize it to facilitate your work. Please join your colleagues by making a donation now and again in the future.

Donations are an important component of our efforts to ensure long-term funding to provide you the information that you need at your fingertips. Toggle navigation. A bonus to all MIMmatch users is the option to sign up for updates on new gene-phenotype relationships. NCBI Gene. Clinical Trials. Gene-Phenotype Relationships.

Hairy ears, Y-linked YL 2. Clinical Synopsis Toggle Dropdown. Looking For More References? Marla J. Creation Date:. Victor A. Clin Exp Dermatol ; 15 : — Am J Hum Genet ; 67 : — Nucl Acids Res ; 30 : e Y Chromosome Consortium. Genome Res ; 12 : — Annu Rev Anthropol ; 31 : — Nature ; : — J Med Genet ; 41 : E Hum Reproduct ; 14 : — Download references. We thank the participants, Professor AS Thambiah for his courtesy in allowing subject recruitment, and Elena Bosch for help with haplotyping.

Virugambakkam, Annamalai Colony, Chennai, , India. You can also search for this author in PubMed Google Scholar. Correspondence to Mark A Jobling. Reprints and Permissions.

Lee, A. Molecular evidence for absence of Y-linkage of the Hairy Ears trait. Eur J Hum Genet 12, — Download citation. Received : 03 May Revised : 10 June Accepted : 25 June Published : 15 September Issue Date : 01 December Anyone you share the following link with will be able to read this content:.

Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. European Journal of Human Genetics Advanced search. Skip to main content Thank you for visiting nature. Download PDF. Abstract The human Hairy Ears phenotype has traditionally been regarded as the only Y-linked heritable trait.

Introduction For over 40 years there has been debate over the mode of inheritance of the human Hairy Ears trait Hypertrichosis Pinnae Auris MIM or , attracting the early interest of such luminaries as Curt Stern 1 , 2 and JBS Haldane, 3 and characterized by the unusual feature of several geneticists studying themselves and their own families.

Materials and methods Buccal swab samples were obtained with informed consent from 50 Hairy-Eared males and 50 unaffected males, both groups being ascertained by visual inspection. Figure 1. Full size image.

Results We hypothesized that if the generally rare trait of Hairy Ears were indeed Y-linked, then manifesting males within a given population would be likely to share the same causative mutation on the Y chromosome. Discussion Given this evidence against Y-linkage, and the obvious influence of hormones upon sexual dimorphism in body-hair patterns, sex-limited expression of an autosomal or pseudoautosomal dominant trait seems the most parsimonious explanation of the mode of inheritance of Hairy Ears in southern Indians.

References 1 Stern C : The problem of complete Y-linkage in man. View author publications. Rights and permissions Reprints and Permissions.

About this article Cite this article Lee, A. Copy to clipboard. Search Search articles by subject, keyword or author.